Our Products

Rotary Evaporator

Laboratory equipment

Jacketed Reactor

Contact Us

We Cherish All Interactions

Contribution of microreactor technology and flow chemistry .

Contribution of microreactor technology and flow chemistry .

Microreactor technology and flow chemistry could play an important role in the development of green and sustainable synthetic processes. In this review, some recent relevant examples in the field of flash chemistry, catalysis, hazardous chemistry and continuous flow processing are described.

tert-Butyl 12-amino-4,7,10-trioxadodecanoate technical .

tert-Butyl 12-amino-4,7,10-trioxadodecanoate technical .

Application tert-Butyl 12-amino-4,7,10-trioxadod ecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are: • Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.

Chemical and biochemical microreactors - ScienceDirect

Chemical and biochemical microreactors - ScienceDirect

Jun 01, 2000 · His current research activities are in the areas of microreactor and μFIA applications, microwave-enhanced reaction chemistry, trace elemental speciation and process analysis. He is author of over 100 research papers, a number of books and patents and is widely known nationally and internationally for his enthusiastic lectures.

About us - Vapourtec

About us - Vapourtec

About us. Vapourtec Ltd is a technology company located near to Cambridge in the UK, with many years of experience producing world leading laboratory equipment for Europe, USA and other regions serving the pharmaceutical drug discovery industry.

Micro reactor and flow chemistry for industrial .

Micro reactor and flow chemistry for industrial .

Apr 01, 2012 · Micro reactor and flow chemistry for industrial applications in drug discovery and development Fast microwave synthesis of Pt-MFI zeolite coatings on silicon micromonoliths: application to VOC catalytic combustion Continuous flow synthesis of β-amino α, β-unsaturated esters in aqueous medium

Continuous‐Flow Microreactor Chemistry under High .

Continuous‐Flow Microreactor Chemistry under High .

Continuous‐Flow Microreactor Chemistry under High‐Temperature/Pressure Conditions . Current status and future prospects for enabling chemistry technology in the drug discovery process, F1000Research, 10.12688 . Evaluation of a Nonresonant Microwave Applicator for Continuous-Flow Chemistry Applications, Organic Process Research .

Drug Discovery & Development - Lehigh University

Drug Discovery & Development - Lehigh University

Biopharmaceutical Drug Development: Attrition Drug Discovery Pre-Clinical 5 years 1.5 years 6 years 2 years 2 years Clinical Trials FDA Review Large Scale Manufacturing / Phase IV IND Submitted NDA Submitted 250 Compounds 5 Compounds 10,000 Com-pounds 1 FDA Approved Drug Quelle: Burrell Report Biotechnology Industry 2006 Phase I 20-100

Flow Photochemistry: Shine Some . - Trends in Chemistry

Flow Photochemistry: Shine Some . - Trends in Chemistry

Continuous-flow chemistry has recently attracted significant interest from chemists in both academia and industry working in different disciplines and from different backgrounds. Flow methods are now being used in reaction discovery/methodology, in scale-up and production, and for rapid screening and optimization. Photochemical processes are currently an important research field in the .

Microreactor Technology | Sigma-Aldrich

Microreactor Technology | Sigma-Aldrich

Designed by chemists for chemists, it contains everything that is needed to perform flow chemistry experiments in a microstructured system right away: robust pumps for the transport of the reagent streams, a microreactor, an electronic monitoring unit including sensors for automated temperature and pressure supervision, sufficient tubing and fittings to connect all the different modules of the system, .

Wiley-VCH - Sustainable Flow Chemistry

Wiley-VCH - Sustainable Flow Chemistry

Chemistry, and a member of the FWO WT&4 Chemistry expert panel and of the OECD-EPA commission on substitution of toxic substances. Prof. Vaccaro is leading the Green S.O.C. group in Perugia and is dedicating his research and teaching activity to the development of sustainable tools for minimizing waste and accessing cleaner products.

Extending the application of biocatalysis to meet the .

Extending the application of biocatalysis to meet the .

Nov 20, 2018 · Stepan, A. F. et al. Late-stage microsomal oxidation reduces drug−drug interaction and identifies phosphodiesterase 2A inhibitor PF-06815189. ACS Med. Chem. Lett. 9, 68–72 (2018).

Flow microreactor synthesis of 2,2-disubstituted oxetanes .

Flow microreactor synthesis of 2,2-disubstituted oxetanes .

3 Results and Discussion. On the basis of previous experience of generating highly unstable oxiranyl [37-39] and aziridinyl lithium species [40, 41] under flow chemistry, our study began by assembling a flow microreactor system that consisted of two T-shaped micromixers (M1 and M2) and two microtube reactors (R1 and R2) as shown in figure 1.A solution of 2-phenyloxetane 1 and a solution of s .

Fluorescence SpectraViewer | Thermo Fisher Scientific - UK

Fluorescence SpectraViewer | Thermo Fisher Scientific - UK

Popular. Popular TaqMan Real-Time PCR Assays Antibodies Oligos, Primers & Probes GeneArt Gene Synthesis Cell Culture Plastics; Applications & Techniques

Why perform your chemistry in continuous flow? - Syrris .

Why perform your chemistry in continuous flow? - Syrris .

May 15, 2018 · The same 10 L of reagents could be passed through a 10 mL flow microreactor chip, ensuring that only 10 mL is reacting at any time. . allowing for the quick identification of lead compounds and is especially useful in drug discovery and development chemistry. . 9 substantial reasons to consider performing your lab's chemistry using .

Journal Rankings on Drug Discovery

Journal Rankings on Drug Discovery

Drug Discovery; Drug Guides; Earth and Planetary Sciences (miscellaneous) Earth-Surface Processes; Ecological Modeling; Ecology; Ecology, Evolution, Behavior and Systematics; Economic Geology; Economics and Econometrics; Economics, Econometrics and Finance (miscellaneous) Education; E-learning; Electrical and Electronic Engineering .

The flow synthesis of heterocycles for natural product and .

The flow synthesis of heterocycles for natural product and .

Oct 20, 2010 · This article represents an overview of recent research from the Innovative Technology Centre in the field of flow chemistry which was presented at the FROST2 meeting in Budapest in October 2009. After a short introduction of this rapidly expanding field, we discuss some of our results with a main focus on the synthesis of heterocyclic compounds which we use in various natural product .

Integration of a Microreactor in an Existing Production .

Integration of a Microreactor in an Existing Production .

Volker Hessel, Patrick Löb, Holger Löwe, Industrial Microreactor Process Development up to Production . Jun‐ichi Yoshida, Industrial Applications of Flash Chemistry, Flash Chemistry, 10.1002 . Charlotte Wiles, Paul Watts, Improving chemical synthesis using flow reactors, Expert Opinion on Drug Discovery, 10.1517/17460441.2.11 .

Flow microreactor synthesis in organo-fluorine chemistry .

Flow microreactor synthesis in organo-fluorine chemistry .

Recently, flow microreactor synthesis has emerged as a new methodology for producing chemical substances with high efficiency. This review outlines the successful examples of synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems to overcome long-standing problems in fluorine chemistry.

Micro reactor and flow chemistry for industrial .

Micro reactor and flow chemistry for industrial .

Apr 01, 2012 · Micro reactor and flow chemistry for industrial applications in drug discovery and development Micro reactor and flow chemistry for industrial applications in drug discovery and development 2012-04-01 00:00:00 Abstract In this review, case studies focused on syntheses of active pharmaceutical ingredients, intermediates and lead compounds are reported employing micro .

Discovery | MercachemSyncom

Discovery | MercachemSyncom

Drug discovery is an interdisciplinary science where experience is key. Our Medicinal Chemistry team combines over 150 years of relevant experience in the pharma industry. We also partner with leading CROs for specific biological platforms, offering a fully integrated solution to your Discovery needs.

Contribution of microreactor technology and flow chemistry .

Contribution of microreactor technology and flow chemistry .

Oct 16, 2017 · With the aim to design more sustainable synthetic processes, we set up, at the Depatment of Pharmacy, a well equipped "flow chemistry laboratory" named FLAME-Lab, for the development of continuous-flow microreactor-mediated organometallic and organocatalytic synthesis in both homegenous and heterogenous conditions. 3. Molecular Dynamics.

Wiley-VCH - Sustainable Flow Chemistry

Wiley-VCH - Sustainable Flow Chemistry

Chemistry, and a member of the FWO WT&4 Chemistry expert panel and of the OECD-EPA commission on substitution of toxic substances. Prof. Vaccaro is leading the Green S.O.C. group in Perugia and is dedicating his research and teaching activity to the development of sustainable tools for minimizing waste and accessing cleaner products.

Contact | Snapdragon Chemistry

Contact | Snapdragon Chemistry

Timothy F. Jamison, Ph.D. Co-Founder and Scientific Advisor A world-renowned expert in flow chemistry, methodology development, and organic synthesis, Tim Jamison founded Snapdragon Chemistry with a vision to enhance the entire drug discovery >> development >> manufacturing value chain through flow chemistry.

Organic synthesis provides opportunities to transform drug .

Organic synthesis provides opportunities to transform drug .

Mar 22, 2018 · Organic synthesis is a rate-limiting factor in drug discovery, so the pharmaceutical industry heavily relies on academic research. This Perspective highlights some of .

Micro reactor and flow chemistry for industrial .

Micro reactor and flow chemistry for industrial .

In this review, case studies focused on syntheses of active pharmaceutical ingredients, intermediates and lead compounds are reported employing micro reactors and continuous flow technology .

Flow microreactor synthesis in organo-fluorine chemistry

Flow microreactor synthesis in organo-fluorine chemistry

Recently, flow microreactor synthesis has emerged as a new methodology for producing chemical substances with high efficiency. This review outlines the successful examples of synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems to overcome long-standing problems in fluorine chemistry.

What is Library Synthesis in Flow Chemistry & how can the .

What is Library Synthesis in Flow Chemistry & how can the .

The automated Asia system is designed for fast, serial library synthesis in flow chemistry and is capable of synthesizing and purifying 10s – 100s of compounds a day. The heart of Asia is a microfluidic reactor through which reactions are flowed.

tks | publisher, event organiser, media agency .

tks | publisher, event organiser, media agency .

The major advantage of microreactor technology (MRT), reflected in high intensification of chemical and biochemical processes, arises from short diffusion paths in the microfluidic devices. However, the greatest opportunities and challenges still lie in the transfer of MRT to a real industrial environment.

Chemical and biochemical microreactors - ScienceDirect

Chemical and biochemical microreactors - ScienceDirect

Jun 01, 2000 · His current research activities are in the areas of microreactor and μFIA applications, microwave-enhanced reaction chemistry, trace elemental speciation and process analysis. He is author of over 100 research papers, a number of books and patents and is widely known nationally and internationally for his enthusiastic lectures.

SELECTBIO - Flow Chemistry Europe Agenda

SELECTBIO - Flow Chemistry Europe Agenda

Flow chemistry/microreactor technology can significantly expand the synthetic arsenal of available chemistries on both lab and process scale. Reactions and reagents previously considered to be too hazardous to be utilized in batch now become available for flow chemistry applications. 15:30. Coffee and Networking in Exhibition Hall . 16:00